Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

BACKGROUND AND PURPOSE: Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of acute liver failure in developed countries. Given the significant limitations associated with N‐acetyl cysteine, the only antidote used to treat AILI, the development of novel therapeutic approaches...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Yan, Mingzhu, Ye, Linhu, Yin, Shutao, Lu, Xiaotong, Liu, Xiaoyi, Lu, Shangyun, Cui, Jinling, Fan, Lihong, Kaplowitz, Neil, Hu, Hongbo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135785/
https://ncbi.nlm.nih.gov/pubmed/30024038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14444
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