High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease

High circulatory insulin and leptin followed by underlying inflammation are often ascribed to the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact molecular pathways remain unclear. We have shown previously that CYP2E1-mediated oxidative stress and circulating leptin...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Alhasson, Firas, Seth, Ratanesh Kumar, Sarkar, Sutapa, Kimono, Diana A., Albadrani, Muayad S., Dattaroy, Diptadip, Chandrashekaran, Varun, Scott, Geoffrey I., Raychoudhury, Samir, Nagarkatti, Mitzi, Nagarkatti, Prakash, Diehl, Anna Mae, Chatterjee, Saurabh
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006523/
https://ncbi.nlm.nih.gov/pubmed/29660503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.002
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