High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease

High circulatory insulin and leptin followed by underlying inflammation are often ascribed to the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact molecular pathways remain unclear. We have shown previously that CYP2E1-mediated oxidative stress and circulating leptin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Redox Biol
Main Authors: Alhasson, Firas, Seth, Ratanesh Kumar, Sarkar, Sutapa, Kimono, Diana A., Albadrani, Muayad S., Dattaroy, Diptadip, Chandrashekaran, Varun, Scott, Geoffrey I., Raychoudhury, Samir, Nagarkatti, Mitzi, Nagarkatti, Prakash, Diehl, Anna Mae, Chatterjee, Saurabh
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2018
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006523/
https://ncbi.nlm.nih.gov/pubmed/29660503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.002
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