Activation of Rho Family GTPases by Small Molecules

[Image: see text] Ras and Ras-related small GTPases are key regulators of diverse cellular functions that impact cell growth, survival, motility, morphogenesis, and differentiation. They are important targets for studies of disease mechanisms as well as drug discovery. Here, we report the characteri...

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Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Palsuledesai, Charuta C., Surviladze, Zurab, Waller, Anna, Miscioscia, T. Fabiola, Guo, Yuna, Wu, Yang, Strouse, Jake, Romero, Elsa, Salas, Virginia M., Curpan, Ramona, Young, Susan, Carter, Mark, Foutz, Terry, Galochkina, Zhanna, Ames, Harold, Haynes, Mark K., Edwards, Bruce S., Nicolotti, Orazio, Luo, Li, Ursu, Oleg, Bologa, Cristian G., Oprea, Tudor I., Wandinger-Ness, Angela, Sklar, Larry A.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2018
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006448/
https://ncbi.nlm.nih.gov/pubmed/29746086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00038
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