Activation of Rho Family GTPases by Small Molecules

[Image: see text] Ras and Ras-related small GTPases are key regulators of diverse cellular functions that impact cell growth, survival, motility, morphogenesis, and differentiation. They are important targets for studies of disease mechanisms as well as drug discovery. Here, we report the characteri...

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發表在:ACS Chem Biol
Main Authors: Palsuledesai, Charuta C., Surviladze, Zurab, Waller, Anna, Miscioscia, T. Fabiola, Guo, Yuna, Wu, Yang, Strouse, Jake, Romero, Elsa, Salas, Virginia M., Curpan, Ramona, Young, Susan, Carter, Mark, Foutz, Terry, Galochkina, Zhanna, Ames, Harold, Haynes, Mark K., Edwards, Bruce S., Nicolotti, Orazio, Luo, Li, Ursu, Oleg, Bologa, Cristian G., Oprea, Tudor I., Wandinger-Ness, Angela, Sklar, Larry A.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2018
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006448/
https://ncbi.nlm.nih.gov/pubmed/29746086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00038
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