Activation of Rho Family GTPases by Small Molecules

[Image: see text] Ras and Ras-related small GTPases are key regulators of diverse cellular functions that impact cell growth, survival, motility, morphogenesis, and differentiation. They are important targets for studies of disease mechanisms as well as drug discovery. Here, we report the characteri...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Palsuledesai, Charuta C., Surviladze, Zurab, Waller, Anna, Miscioscia, T. Fabiola, Guo, Yuna, Wu, Yang, Strouse, Jake, Romero, Elsa, Salas, Virginia M., Curpan, Ramona, Young, Susan, Carter, Mark, Foutz, Terry, Galochkina, Zhanna, Ames, Harold, Haynes, Mark K., Edwards, Bruce S., Nicolotti, Orazio, Luo, Li, Ursu, Oleg, Bologa, Cristian G., Oprea, Tudor I., Wandinger-Ness, Angela, Sklar, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006448/
https://ncbi.nlm.nih.gov/pubmed/29746086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00038
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