Hyperhaploidy is a Novel High-Risk Cytogenetic Subgroup in Multiple Myeloma

Hyperhaploid clones (24-34 chromosomes) were identified in 33 patients with multiple myeloma (MM), identifying a novel numerical cytogenetic subgroup. Strikingly, all hyperhaploid karyotypes were found to harbor monosomy 17p, the single most important risk stratification lesion in MM. A catastrophic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Leukemia
Main Authors: Sawyer, Jeffrey R., Tian, Erming, Shaughnessy, John D., Epstein, Joshua, Swanson, Charles M., Stangeby, Collin, Hale, Christine L., Parr, Lewis, Lynn, Michael, Sammartino, Gael, Lukacs, Janet L., Stein, Caleb, Bailey, Clyde, Zangari, Maurizio, Davies, Faith E., Van Rhee, Frits, Barlogie, Bart, Morgan, Gareth J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005364/
https://ncbi.nlm.nih.gov/pubmed/27694925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.253
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares