Hyperhaploidy is a Novel High-Risk Cytogenetic Subgroup in Multiple Myeloma

Hyperhaploid clones (24-34 chromosomes) were identified in 33 patients with multiple myeloma (MM), identifying a novel numerical cytogenetic subgroup. Strikingly, all hyperhaploid karyotypes were found to harbor monosomy 17p, the single most important risk stratification lesion in MM. A catastrophic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Leukemia
Prif Awduron: Sawyer, Jeffrey R., Tian, Erming, Shaughnessy, John D., Epstein, Joshua, Swanson, Charles M., Stangeby, Collin, Hale, Christine L., Parr, Lewis, Lynn, Michael, Sammartino, Gael, Lukacs, Janet L., Stein, Caleb, Bailey, Clyde, Zangari, Maurizio, Davies, Faith E., Van Rhee, Frits, Barlogie, Bart, Morgan, Gareth J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005364/
https://ncbi.nlm.nih.gov/pubmed/27694925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.253
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