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Targeting Rac and Cdc42 GTPases in Cancer
Rac and Cdc42 are small GTPases that have been linked to multiple human cancers, and implicated in epithelial to mesenchymal transition, cell cycle progression, migration/invasion, tumor growth, angiogenesis, and oncogenic transformation. With the exception of the P29S driver mutation in melanoma, R...
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| Veröffentlicht in: | Cancer Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6004249/ https://ncbi.nlm.nih.gov/pubmed/29858187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0619 |
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