Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury

Podocytes are highly specialized epithelial cells with complex actin cytoskeletal architecture crucial for maintenance of the glomerular filtration barrier. The mammalian Rho GTPases Rac1 and Cdc42 are molecular switches that control many cellular processes, but are best known for their roles in the...

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Autori principali: Blattner, Simone M., Hodgin, Jeffrey B., Nishio, Masashi, Wylie, Stephanie, Saha, Jharna, Soofi, Abdul, Vining, Courtenay, Randolph, Ann, Herbach, Nadja, Wanke, Ruediger, Atkins, Kevin B., Kang, Hee Gyung, Henger, Anna, Brakebusch, Cord, Holzman, Lawrence B., Kretzler, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815690/
https://ncbi.nlm.nih.gov/pubmed/23677246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.175
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