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Targeting Rac and Cdc42 GEFs in Metastatic Cancer
The Rho family GTPases Rho, Rac, and Cdc42 have emerged as key players in cancer metastasis, due to their essential roles in regulating cell division and actin cytoskeletal rearrangements; and thus, cell growth, migration/invasion, polarity, and adhesion. This review will focus on the close homologs...
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| Vydáno v: | Front Cell Dev Biol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7156542/ https://ncbi.nlm.nih.gov/pubmed/32322580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00201 |
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