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Targeting Rac and Cdc42 GTPases in Cancer

Rac and Cdc42 are small GTPases that have been linked to multiple human cancers, and implicated in epithelial to mesenchymal transition, cell cycle progression, migration/invasion, tumor growth, angiogenesis, and oncogenic transformation. With the exception of the P29S driver mutation in melanoma, R...

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Dades bibliogràfiques
Publicat a:Cancer Res
Autors principals: del Mar Maldonado, María, Dharmawardhane, Suranganie
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004249/
https://ncbi.nlm.nih.gov/pubmed/29858187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0619
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