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Targeting Rac and Cdc42 GTPases in Cancer

Rac and Cdc42 are small GTPases that have been linked to multiple human cancers, and implicated in epithelial to mesenchymal transition, cell cycle progression, migration/invasion, tumor growth, angiogenesis, and oncogenic transformation. With the exception of the P29S driver mutation in melanoma, R...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: del Mar Maldonado, María, Dharmawardhane, Suranganie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004249/
https://ncbi.nlm.nih.gov/pubmed/29858187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0619
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