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Codon usage of highly expressed genes affects proteome-wide translation efficiency
Although the genetic code is redundant, synonymous codons for the same amino acid are not used with equal frequencies in genomes, a phenomenon termed “codon usage bias.” Previous studies have demonstrated that synonymous changes in a coding sequence can exert significant cis effects on the gene’s ex...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003480/ https://ncbi.nlm.nih.gov/pubmed/29735666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719375115 |
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