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Dynamic changes in translational efficiency are deduced from codon usage of the transcriptome
Translation of a gene is assumed to be efficient if the supply of the tRNAs that translate it is high. Yet high-abundance tRNAs are often also at high demand since they correspond to preferred codons in genomes. Thus to fully model translational efficiency one must gauge the supply-to-demand ratio o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488229/ https://ncbi.nlm.nih.gov/pubmed/22941644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks772 |
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