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Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency

Cellular efficiency in protein translation is an important fitness determinant in rapidly growing organisms. It is widely believed that synonymous codons are translated with unequal speeds and that translational efficiency is maximized by the exclusive use of rapidly translated codons. Here we estim...

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Main Authors: Qian, Wenfeng, Yang, Jian-Rong, Pearson, Nathaniel M., Maclean, Calum, Zhang, Jianzhi
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315465/
https://ncbi.nlm.nih.gov/pubmed/22479199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002603
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