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The role of codon selection in regulation of translation efficiency deduced from synthetic libraries

BACKGROUND: Translation efficiency is affected by a diversity of parameters, including secondary structure of the transcript and its codon usage. Here we examine the effects of codon usage on translation efficiency by re-analysis of previously constructed synthetic expression libraries in Escherichi...

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Autores principales: Navon, Sivan, Pilpel, Yitzhak
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188794/
https://ncbi.nlm.nih.gov/pubmed/21284851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-2-r12
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