Codon usage can affect efficiency of translation of genes in Escherichia coli.

By inserting synthetic oligonucleotides into a highly expressed gene in E. coli it has been shown that unfavourable codon usage can reduce the maximum translation rate of a protein. However, in the case of the codon used (AGG), a significant effect on translation was only seen at very high transcrip...

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Библиографические подробности
Главные авторы: Robinson, M, Lilley, R, Little, S, Emtage, J S, Yarranton, G, Stephens, P, Millican, A, Eaton, M, Humphreys, G
Формат: Artigo
Язык:Inglês
Опубликовано: 1984
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC320107/
https://ncbi.nlm.nih.gov/pubmed/6091031
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