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Codon usage can affect efficiency of translation of genes in Escherichia coli.

By inserting synthetic oligonucleotides into a highly expressed gene in E. coli it has been shown that unfavourable codon usage can reduce the maximum translation rate of a protein. However, in the case of the codon used (AGG), a significant effect on translation was only seen at very high transcrip...

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Udgivet i:Nucleic Acids Res
Principais autores: Robinson, M, Lilley, R, Little, S, Emtage, J S, Yarranton, G, Stephens, P, Millican, A, Eaton, M, Humphreys, G
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1984
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6091031/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.17.6663
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