Codon usage can affect efficiency of translation of genes in Escherichia coli.
By inserting synthetic oligonucleotides into a highly expressed gene in E. coli it has been shown that unfavourable codon usage can reduce the maximum translation rate of a protein. However, in the case of the codon used (AGG), a significant effect on translation was only seen at very high transcrip...
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| Опубліковано в:: | Nucleic Acids Res |
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| Автори: | , , , , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Oxford University Press
1984
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| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6091031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.17.6663 |
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