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[(18)F]ODIBO: a universal prosthetic group for highly efficient radiolabelling of macromolecules via strain-promoted alkyne-azide cycloaddition

A novel prosthetic group for efficient radiolabeling of macromolecules have been developed. [(18)F]oxadibenzocyclooctyne ([(18)F]ODIBO) is synthesized in high radiochemical yield and applied for nearly quantitative conjugation to azide-tagged peptides and proteins at room temperature and low substra...

詳細記述

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書誌詳細
出版年:Org Biomol Chem
主要な著者: Boudjemeline, Mehdi, McNitt, Christopher D., Popik, Vladimir V., Kostikov, Alexey P.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999037/
https://ncbi.nlm.nih.gov/pubmed/29170778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob02532g
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