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lFacile quenching and spatial patterning of cylooctynes via strain-promoted alkyne–azide cycloaddition of inorganic azides

Little is known about the reactivity of strain-promoted alkyne–azide cycloaddition (SPAAC) reagents with inorganic azides. We explore the reactions of a variety of popular SPAAC reagents with sodium azide and hydrozoic acid. We find that the reactions proceed in water at rates comparable to those wi...

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Vydáno v:Bioconjug Chem
Hlavní autoři: Bjerknes, Matthew, Cheng, Hazel, McNitt, Christopher D., Popik, Vladimir V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991799/
https://ncbi.nlm.nih.gov/pubmed/28437092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00201
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