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Structural Determinants of Alkyne Reactivity in Copper-Catalyzed Azide-Alkyne Cycloadditions

This work represents our initial effort in identifying azide/alkyne pairs for optimal reactivity in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. In previous works, we have identified chelating azides, in particular 2-picolyl azide, as “privileged” azide substrates with high CuAAC r...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Xiaoguang, Liu, Peiye, Zhu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274337/
https://ncbi.nlm.nih.gov/pubmed/27941684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121697
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