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Relative Performance of Alkynes in Copper-Catalyzed Azide-Alkyne Cycloaddition

Copper-catalyzed azide–alkyne cycloaddition (CuAAC) has found numerous applications in a variety of fields. We report here only modest differences in the reactivity of various classes of terminal alkynes under typical bioconjugative and preparative organic conditions. Propargyl compounds represent a...

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Main Authors: Kislukhin, Alexander A., Hong, Vu P., Breitenkamp, Kurt E., Finn, M.G.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170714/
https://ncbi.nlm.nih.gov/pubmed/23566039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300672b
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