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Labeling Live Cells by Copper-Catalyzed Alkyne-Azide Click Chemistry

The copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, optimized for biological molecules in aqueous buffers, has been shown to rapidly label mammalian cells in culture with no loss in cell viability. Metabolic uptake and display of the azide derivative of N-acetylmannosamine developed by...

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Sonraí Bibleagrafaíochta
Main Authors: Hong, Vu, Steinmetz, Nicole F., Manchester, Marianne, Finn, M.G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014321/
https://ncbi.nlm.nih.gov/pubmed/20886827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc100272z
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