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Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne-Azide Cycloaddition

Artificial systems for controlled membrane fusion applicable for drug delivery would ideally use triggers that are orthogonal to biology. To apply the strain-promoted alkyneazide cycloaddition (SPAAC) to drive membrane fusion, ODIBO lipid 1 was designed, synthesized and studied alongside ADIBO-lipid...

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Bibliografische gegevens
Gepubliceerd in:Bioconjug Chem
Hoofdauteurs: Whitehead, Stuart A., McNitt, Christopher D., Mattern Schain, Samuel I., Carr, Adam J., Alam, Shahrina, Popik, Vladimir V., Best, Michael D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990007/
https://ncbi.nlm.nih.gov/pubmed/28248084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00578
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