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[(18)F]ODIBO: a universal prosthetic group for highly efficient radiolabelling of macromolecules via strain-promoted alkyne-azide cycloaddition
A novel prosthetic group for efficient radiolabeling of macromolecules have been developed. [(18)F]oxadibenzocyclooctyne ([(18)F]ODIBO) is synthesized in high radiochemical yield and applied for nearly quantitative conjugation to azide-tagged peptides and proteins at room temperature and low substra...
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| Publicado en: | Org Biomol Chem |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5999037/ https://ncbi.nlm.nih.gov/pubmed/29170778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob02532g |
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