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Photochemical Generation of Oxa-Dibenzocyclooctyne (ODIBO) for Metal-Free Click Ligations

Oxa-dibenzocyclooctynes (ODIBO, 2a–c) are prepared by photochemical decarbonylation of corresponding cyclopropenones (photo-ODIBO, 1a–c). While photo-ODIBO does not react with azides, ODIBO is one of the most reactive cyclooctynes exhibiting rates of cycloaddition over 45 M(−1)s(−1) in aqueous solut...

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Bibliografische gegevens
Gepubliceerd in:Org Biomol Chem
Hoofdauteurs: McNitt, Christopher D., Popik, Vladimir V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992911/
https://ncbi.nlm.nih.gov/pubmed/22987146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26581h
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