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Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema

Cigarette smoke (CS) induces lung cellular senescence that plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). How aging influences cellular senescence and other molecular hallmarks, and increases the risk of CS-induced damage remains unknown. We hypothesized...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Rashid, Kahkashan, Sundar, Isaac K., Gerloff, Janice, Li, Dongmei, Rahman, Irfan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998122/
https://ncbi.nlm.nih.gov/pubmed/29899396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27209-3
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