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Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema

Cigarette smoke (CS) induces lung cellular senescence that plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). How aging influences cellular senescence and other molecular hallmarks, and increases the risk of CS-induced damage remains unknown. We hypothesized...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rashid, Kahkashan, Sundar, Isaac K., Gerloff, Janice, Li, Dongmei, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998122/
https://ncbi.nlm.nih.gov/pubmed/29899396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27209-3
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