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Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis

BACKGROUND: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric leng...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://ncbi.nlm.nih.gov/pubmed/33013423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.584637
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