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Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis

BACKGROUND: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric leng...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://ncbi.nlm.nih.gov/pubmed/33013423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.584637
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