Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma

BACKGROUND: Patients with severe asthma may have a greater risk of dying from COVID-19 disease. Angiotensin converting enzyme-2 (ACE2) and the enzyme proteases, transmembrane protease serine 2 (TMPRSS2) and FURIN, are needed for viral attachment and invasion into host cells. METHODS: We examined mic...

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Vydáno v:Respir Res
Hlavní autoři: Kermani, Nazanin Zounemat, Song, Woo-Jung, Badi, Yusef, Versi, Ali, Guo, Yike, Sun, Kai, Bhavsar, Pank, Howarth, Peter, Dahlen, Sven-Erik, Sterk, Peter J., Djukanovic, Ratko, Adcock, Ian M., Chung, Kian Fan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788167/
https://ncbi.nlm.nih.gov/pubmed/33413387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01605-8
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