Sputum ACE2, TMPRSS2 and FURIN gene expression in severe neutrophilic asthma

BACKGROUND: Patients with severe asthma may have a greater risk of dying from COVID-19 disease. Angiotensin converting enzyme-2 (ACE2) and the enzyme proteases, transmembrane protease serine 2 (TMPRSS2) and FURIN, are needed for viral attachment and invasion into host cells. METHODS: We examined mic...

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Publicado en:Respir Res
Autores principales: Kermani, Nazanin Zounemat, Song, Woo-Jung, Badi, Yusef, Versi, Ali, Guo, Yike, Sun, Kai, Bhavsar, Pank, Howarth, Peter, Dahlen, Sven-Erik, Sterk, Peter J., Djukanovic, Ratko, Adcock, Ian M., Chung, Kian Fan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7788167/
https://ncbi.nlm.nih.gov/pubmed/33413387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01605-8
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