Instability of sputum molecular phenotypes in U-BIOPRED severe asthma

At 1 year, 45% of severe asthma change molecular phenotype as determined by sputum transcriptomic analysis. Together with concomitant shift in sputum granulocytic markers, this may indicate variability of driving mechanisms in this unstable group. https://bit.ly/35aj489

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Kermani, Nazanin Z., Pavlidis, Stelios, Xie, Jiaxing, Sun, Kai, Loza, Matthew, Baribaud, Fred, Fowler, Steve J., Shaw, Dominic E., Fleming, Louise J., Howarth, Peter H., Sousa, Ana R., Corfield, Julie, Auffray, Charles, De Meulder, Bertrand, Sterk, Peter J., Guo, Yike, Uddin, Mohib, Djukanovic, Ratko, Adcock, Ian M., Chung, Kian Fan
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2021
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Agora
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859503/
https://ncbi.nlm.nih.gov/pubmed/33008937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01836-2020
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