Instability of sputum molecular phenotypes in U-BIOPRED severe asthma

At 1 year, 45% of severe asthma change molecular phenotype as determined by sputum transcriptomic analysis. Together with concomitant shift in sputum granulocytic markers, this may indicate variability of driving mechanisms in this unstable group. https://bit.ly/35aj489

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Dettagli Bibliografici
Pubblicato in:Eur Respir J
Autori principali: Kermani, Nazanin Z., Pavlidis, Stelios, Xie, Jiaxing, Sun, Kai, Loza, Matthew, Baribaud, Fred, Fowler, Steve J., Shaw, Dominic E., Fleming, Louise J., Howarth, Peter H., Sousa, Ana R., Corfield, Julie, Auffray, Charles, De Meulder, Bertrand, Sterk, Peter J., Guo, Yike, Uddin, Mohib, Djukanovic, Ratko, Adcock, Ian M., Chung, Kian Fan
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Respiratory Society 2021
Soggetti:
Agora
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859503/
https://ncbi.nlm.nih.gov/pubmed/33008937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01836-2020
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