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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Cigarette smoke is a major etiological risk factor that has been shown to alter cellular processes involving mitochondrial function, cellular senescence and te...

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Détails bibliographiques
Publié dans:medRxiv
Auteurs principaux: Maremanda, Krishna P, Sundar, Isaac Kirubakaran, Li, Dongmei, Rahman, Irfan
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310643/
https://ncbi.nlm.nih.gov/pubmed/32587985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.14.20129957
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