Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis

BACKGROUND: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric leng...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://ncbi.nlm.nih.gov/pubmed/33013423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.584637
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