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Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis

BACKGROUND: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric leng...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Maremanda, Krishna P., Sundar, Isaac K., Li, Dongmei, Rahman, Irfan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510459/
https://ncbi.nlm.nih.gov/pubmed/33013423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.584637
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