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Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells
Loss of peroxisome proliferator-activated receptor γ (PPARγ) has been found to contribute to pulmonary artery smooth muscle cell (PASMC) proliferation and pulmonary arterial remodeling therefore the development of pulmonary hypertension (PH). Yet, the molecular mechanisms underlying PPARγ reduction...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5996952/ https://ncbi.nlm.nih.gov/pubmed/29212876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-03-0141 |
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