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Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells

Loss of peroxisome proliferator-activated receptor γ (PPARγ) has been found to contribute to pulmonary artery smooth muscle cell (PASMC) proliferation and pulmonary arterial remodeling therefore the development of pulmonary hypertension (PH). Yet, the molecular mechanisms underlying PPARγ reduction...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Xie, Xinming, Li, Shaojun, Zhu, Yanting, Liu, Lu, Ke, Rui, Wang, Jian, Yan, Xin, Yang, Lan, Gao, Li, Zang, Weijin, Li, Manxiang
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996952/
https://ncbi.nlm.nih.gov/pubmed/29212876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-03-0141
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