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Activation of peroxisome proliferator-activated receptor γ ameliorates monocrotaline-induced pulmonary arterial hypertension in rats

Activation of peroxisome proliferator-activated receptor γ (PPARγ) suppresses the proliferation of pulmonary artery smooth muscle cells (PASMCs) and vascular remodeling in rats and humans, and therefore improves the development of pulmonary arterial hypertension (PAH). However, molecular mechanisms...

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: XIE, XINMING, WANG, GUIZUO, ZHANG, DEXIN, ZHANG, YONGHONG, ZHU, YANTING, LI, FANGWEI, LI, SHAOJUN, LI, MANXIANG
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487024/
https://ncbi.nlm.nih.gov/pubmed/26171162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2015.465
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