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Peroxisome Proliferator‐activated Receptor‐γ Agonist Pioglitazone Ameliorates White Matter Lesion and Cognitive Impairment in Hypertensive Rats

AIMS: Cerebrovascular white matter lesion (WML) is a major subtype of cerebral small vessel disease. Clinical drugs are not available for WML. We investigated whether peroxisome proliferator‐activated receptor‐γ agonist pioglitazone, with properties of vascular protection and antiinflammation, exert...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Lan, Lin‐Fang, Zheng, Lu, Yang, Xian, Ji, Xiao‐Tan, Fan, Yu‐Hua, Zeng, Jin‐Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495406/
https://ncbi.nlm.nih.gov/pubmed/25611692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12374
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