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Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27Kip1 Signaling Pathway

It has been shown that activation of adenosine monophosphate-activated protein kinase (AMPK) suppresses proliferation of a variety of tumor cells as well as nonmalignant cells. In this study, we used post-transcriptional gene silencing with small interfering RNA (siRNA) to specifically examine the e...

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Autors principals: Rui Ke, Lu Liu, Yanting Zhu, Shaojun Li, Xinming Xie, Fangwei Li, Yang Song, Lan Yang, Li Gao, Manxiang Li
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2016-05-01
Col·lecció:International Journal of Molecular Sciences
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Accés en línia:http://www.mdpi.com/1422-0067/17/6/844
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