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Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells

Loss of peroxisome proliferator-activated receptor γ (PPARγ) has been found to contribute to pulmonary artery smooth muscle cell (PASMC) proliferation and pulmonary arterial remodeling therefore the development of pulmonary hypertension (PH). Yet, the molecular mechanisms underlying PPARγ reduction...

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Detaylı Bibliyografya
Yayımlandı:Mol Biol Cell
Asıl Yazarlar: Xie, Xinming, Li, Shaojun, Zhu, Yanting, Liu, Lu, Ke, Rui, Wang, Jian, Yan, Xin, Yang, Lan, Gao, Li, Zang, Weijin, Li, Manxiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5996952/
https://ncbi.nlm.nih.gov/pubmed/29212876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-03-0141
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