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Autophagy regulates exosomal release of prions in neuronal cells
Prions are protein-based infectious agents that autocatalytically convert the cellular prion protein PrP(C) to its pathological isoform PrP(Sc). Subsequent aggregation and accumulation of PrP(Sc) in nervous tissues causes several invariably fatal neurodegenerative diseases in humans and animals. Pri...
Tallennettuna:
| Julkaisussa: | J Biol Chem |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995502/ https://ncbi.nlm.nih.gov/pubmed/29700113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000713 |
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