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Autophagy pathways in the treatment of prion diseases
Prions use cellular machineries for autocatalytic propagation by conformational conversion of the cellular prion protein into the pathological isoform PrP(Sc). Autophagy is a basic cellular degradation and recycling machinery that delivers cargo to lysosomes. Increase of autophagic flux in cells res...
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| Publicado no: | Curr Opin Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610235/ https://ncbi.nlm.nih.gov/pubmed/31096117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2019.04.013 |
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