SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair

The chromatin remodeling factor SMARCAD1, an SWI/SNF ATPase family member, has a role in 5′ end resection at DNA double-strand breaks (DSBs) to produce single-strand DNA (ssDNA), a critical step for subsequent checkpoint and repair factor loading to remove DNA damage. However, the mechanistic detail...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:iScience
Autori principali: Chakraborty, Sharmistha, Pandita, Raj K., Hambarde, Shashank, Mattoo, Abid R., Charaka, Vijaya, Ahmed, Kazi M., Iyer, Swaminathan P., Hunt, Clayton R., Pandita, Tej K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993204/
https://ncbi.nlm.nih.gov/pubmed/29888761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.03.016
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi