Role of 53BP1 in the Regulation of DNA Double-Strand Break Repair Pathway Choice

The p53-binding protein 1 (53BP1) is a well-known DNA damage response (DDR) factor, which is recruited to nuclear structures at the site of DNA damage and forms readily visualized ionizing radiation (IR) induced foci. Depletion of 53BP1 results in cell cycle arrest in G(2)/M phase as well as genomic...

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Main Authors: Gupta, Arun, Hunt, Clayton R., Chakraborty, Sharmistha, Pandita, Raj K., Yordy, John, Ramnarain, Deepti B., Horikoshi, Nobuo, Pandita, Tej K.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133096/
https://ncbi.nlm.nih.gov/pubmed/24320053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13572.1
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