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Role of 53BP1 in the Regulation of DNA Double-Strand Break Repair Pathway Choice
The p53-binding protein 1 (53BP1) is a well-known DNA damage response (DDR) factor, which is recruited to nuclear structures at the site of DNA damage and forms readily visualized ionizing radiation (IR) induced foci. Depletion of 53BP1 results in cell cycle arrest in G(2)/M phase as well as genomic...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133096/ https://ncbi.nlm.nih.gov/pubmed/24320053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13572.1 |
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