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MOF phosphorylation by ATM regulates 53BP1-mediated DSB repair pathway choice
Cell cycle phase is a critical determinant of the choice between DNA damage repair by non-homologous end joining (NHEJ) or homologous recombination (HR). Here we report that DSBs induce ATM-dependent MOF (a histone H4 acetyl-transferase) phosphorylation (p-T392-MOF) and that phosphorylated MOF co-lo...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300955/ https://ncbi.nlm.nih.gov/pubmed/24953651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.044 |
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