Complement factor H protects mice from ischemic acute kidney injury but is not critical for controlling complement activation by glomerular IgM

Natural IgM binds to glomerular epitopes in several progressive kidney diseases. Previous work has shown that IgM also binds within the glomerulus after ischemia/reperfusion (I/R) but does not fully activate the complement system. Factor H is a circulating complement regulatory protein, and congenit...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Eur J Immunol
Autores principales: Goetz, Lindsey, Laskowski, Jennifer, Renner, Brandon, Pickering, Matthew C., Kulik, Liudmila, Klawitter, Jelena, Stites, Erik, Christians, Uwe, van der Vlag, Johan, Ravichandran, Kameswaran, Holers, V. Michael, Thurman, Joshua M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992014/
https://ncbi.nlm.nih.gov/pubmed/29389016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747240
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares