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IgM exacerbates glomerular disease progression in complement induced glomerulopathy

While glomerular IgM deposition occurs in a variety of glomerular diseases the mechanism of deposition and its clinical significance remain controversial. Some have theorized IgM becomes passively trapped in areas of glomerulosclerosis. However, recent studies found that IgM specifically binds damag...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Panzer, Sarah E., Laskowski, Jennifer, Renner, Brandon, Kulik, Liudmila, Ljubanovic, Danica, Huber, Kendra M., Zhong, Weixiong, Pickering, Matthew C., Holers, V. Michael, Thurman, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556608/
https://ncbi.nlm.nih.gov/pubmed/25945405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.120
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