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Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells

Cardiac differentiation efficiency is hampered by inconsistencies and low reproducibility. We analyzed the differentiation process of multiple human pluripotent stem cell (hPSC) lines in response to dynamic GSK3β inhibition under varying cell culture conditions. hPSCs showed strong differences in ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Laco, Filip, Woo, Tsung Liang, Zhong, Qixing, Szmyd, Radoslaw, Ting, Sherwin, Khan, Fahima Jaleel, Chai, Christina L.L., Reuveny, Shaul, Chen, Allen, Oh, Steve
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989659/
https://ncbi.nlm.nih.gov/pubmed/29706502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.023
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