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Effect of Gsk3 inhibitor CHIR99021 on aneuploidy levels in rat embryonic stem cells

Germline competent embryonic stem (ES) cells can serve as a tool to create genetically engineered rat strains used to elucidate gene function or provide disease models. In optimum culture conditions, ES cells are able to retain their pluripotent state. The type of components present and their concen...

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Main Authors: Bock, Anagha S., Leigh, Nathan D., Bryda, Elizabeth C.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062835/
https://ncbi.nlm.nih.gov/pubmed/24519175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-014-9734-5
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