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Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells

Cardiac differentiation efficiency is hampered by inconsistencies and low reproducibility. We analyzed the differentiation process of multiple human pluripotent stem cell (hPSC) lines in response to dynamic GSK3β inhibition under varying cell culture conditions. hPSCs showed strong differences in ce...

詳細記述

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書誌詳細
出版年:Stem Cell Reports
主要な著者: Laco, Filip, Woo, Tsung Liang, Zhong, Qixing, Szmyd, Radoslaw, Ting, Sherwin, Khan, Fahima Jaleel, Chai, Christina L.L., Reuveny, Shaul, Chen, Allen, Oh, Steve
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989659/
https://ncbi.nlm.nih.gov/pubmed/29706502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.03.023
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